Abstract Mediterranean agroecosystems are under increasing pressures by extreme weather events, which together with poor livestock grazing management bring the already degraded t5 ballast lands closer to desertification.To address these challenges, we develop a decision support manual for sustainable management of degraded lands based on local plan
Immune checkpoint inhibitors as the second-line treatment for advanced esophageal squamous cell carcinoma: a cost-effectiveness analysis based on network meta-analysis
Abstract Background Immune checkpoint inhibitors (ICIs) have demonstrated superior clinical efficacy in prolonging overall survival (OS) as the second-line treatment for advanced or metastatic esophageal squamous cell carcinoma (ESCC), and t5 ballast were recommended by the guidelines.However, it remains uncertain which ICI is the most cost-effecti
Monitoring of the Parasite Load in the Digestive Tract of Rhodnius prolixus by Combined qPCR Analysis and Imaging Techniques Provides New Insights into the Trypanosome Life Cycle.
Here we report the monitoring of the digestive tract colonization of Rhodnius prolixus by Trypanosoma cruzi using an accurate determination of the parasite load by qPCR coupled with fluorescence and bioluminescence imaging (BLI).These complementary methods revealed critical steps necessary for the parasite population to colonize the insect gut and